Itinerary of Dr. Polak presents abundant knowledge concerning hygiene and remedy in Qajar era. It has two special features. First, the author is a doctor. Second, the book is full of detailed but widespread information. The article presents data related to Hygiene and remedy in Dr. Polak’s book briefly, categorized and arranged in four parts: Personal hygiene, Public hygiene, keeping public places clean, status of medical treatment and the government’s attention to Hygiene, remedy and teaching medical profession.